Ophthalmology

CELL CULTURE FOR OCULAR RESEARCH

 

Around the world, millions of patients currently suffer from incurable vision loss. Vision impairing diseases are becoming more common as the population ages. In aging societies, disorders such as macular degeneration or retinitis pigmentosa constitute a leading cause of disability. Globally, the prevalence of ocular diseases is constantly rising. For most of them, there is no effective therapy available. Scientists are trying to accelerate the conversion of basic research on origins of ocular diseases into innovative treatments which change the field of ophthalmic therapy.
 
CELLnTEC offer products for ocular cell isolation, 2D/3D culture and in vitro modeling.

 
HCEP

Primary human corneal cells HCEP growing in the serum-free proliferation medium CnT-PR

 
 
 
LimbalSC

Limbal SCs derived from human iPSC using a protocol based on CnT-30 medium

 

SCIENTIFIC LITERATURE

 

CELLnTEC products deployed for ocular cell isolation, 2D/3D culture and in vitro modeling:

 

Ocular Cell Culture/Modeling CELLnTEC Product Used Article Link
iPSC/ESC differentiation CnT-PR-EF Nakagawa et al. 2025
Primary human limbal epithelial cells proliferation CnT-PR Lee et al. 2025
iPSC-derived human corneal or limbal epithelial cells CnT-30, CnT-07 Kauppila et al. 2025
HCEP to generate a bioengineered cornea model HCEP Kim et al. 2025
Culture of immortalized human conjunctival epithelial cells (iHCjEC) CnT-PR-D Takezawa et al et al. 2024
Isolation and culture of porcine limbal epithelial stem cells CnT-PR-HC, CnT-XP3 Pietryga et al. 2024
Corneal epithelial cell differentiation of ESC CnT-PR Zhang et al. 2024
iPSC to corneal epithelial cells differentiation CnT-30 Kauppila et al. 2023
Isolation and culture of limbal melanocytes CnT-40 Polisetti et al. 2023
Primary human corneal limbal epithelial cells proliferation CnT-57 Volatier et al. 2023
Primary murine corneal epithelial cells proliferation CnT-PR-F Komai et al. 2023
Human corneal epithelial cell isolation and culture CnT-PR Saccu et al. 2022
3D models of cornea and culture of reconstructed corneal epithelium CnT-PR-3D, CnT-PR Chacón et al. 2022
Co-culture of corneal melanoctes and corneal epithelial cells CnT-40, CnT-PR-KM Shen Li et al. 2022
Differentiation of hiPSCs into ocular ectodermal cells CnT-PR-EF Hayashi et al. 2022
Differentiation of human pluripotent stem cells towards limbal stem cells CnT-07, CnT-30 Vattulainen et al. 2021
Differentiation of ESC to limbal cells CnT-30 Sun et al. 2021
Conjunctival epithelial cells isolation and culture CnT-PR Ueta et al. 2020
Differentiation and culture of iPSC derived corneal epithelial cells CnT-07, CnT-PR-EF Okubo et al. 2020
Limbal stem cell culture CnT-PR Hristova et al. 2020
Isolation and culture of melanocytes from human cornea CnT-40 Polisetti et al. 2020
Isolation and culture of limbal epithelial cells CnT-PR Acker et al. 2019

 

Ophthalmology
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