CELLnTEC / Products / CnT-PR-MD


  • Isolation
  • Expansion
  • Differentiation
  • Homeostasis
  • Cryopreservation
  • Co-culture
  • Aging
  • Staining

CnT-Prime Melanocyte Differentiation Medium

media designed for the differentiation of melanocytes and the production of higher levels of melanin and dendrites.

Catalog CnT-PR-MD
Content 500 ml, Frozen medium


  • Specifically designed for differentiation of melanocytes
  • Designed for increased melanin production
  • Fully supplemented, one bottle ready-to-use


The CnT-PR-MD medium is specifically formulated to encourage differentiation, melanin expression, and dendricity in primary melanocytes.

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Tissue type
Low Bovine
Free of Human & Animal Component
Chemically defined
Clinically upgradable
Yes, Serum needs to be supplemented by the user.
500 ml
Frozen Bottle & Ready-to-use
Quality level
Research Grade

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Scientific resources

Total Melanin

Differentiation and melanin expression is increased 2.5x after melanocytes are switched to CnT-PR-MD Melanocyte Differentiation medium.

CnT-PR-MD medium is specifically tailored to create the ideal environment for melanocyte differentiation. It is a fully supplemented, frozen, and ready to use culture medium. It does not contain or antibiotics / antimycotics and is free of PMA and TPA.It differs from standard melanocyte media, which contain a mixture of signals and aim to provide both proliferation and melanin expression in parallel. However, the cells do not receive such mixed signals in vivo and are unable to provide both these behaviours optimally at the same time.

As a result of this focused formulation, CnT-PR-MD delivers 2.5x more melanin and increased dendricity compared with the proliferative CnT-40 medium.

CnT-PR-MD may also be used in conjunction with the CnT-PR-MH Melanocyte Homeostasis medium when conducting melanocyte whitening assays.

Like to try a test sample? Click here for more information.

Thawing, seeding, and passaging protocols are particularly important for optimal cell growth. Please visit our Protocols Page for our recommendations.

It can easily be upgraded for clinical applications. Contact us at support@cellntec.com for further details and pricing.

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Scientific Literature

Title Authors Year Tissue type
Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin Melissa Crawford, Valerie Leclerc, Kevin Barr, Lina Dagnino 2020 Melanocyte
Title Year
CELLnTEC Catalog 2023 Download

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