- Specifically designed for differentiation of melanocytes
- Designed for increased melanin production
- Fully supplemented, one bottle ready-to-use
media designed for the differentiation of melanocytes and the production of higher levels of melanin and dendrites.
|Content||500 ml, Frozen medium|
The CnT-PR-MD medium is specifically formulated to encourage differentiation, melanin expression, and dendricity in primary melanocytes.
CnT-PR-MD medium is specifically tailored to create the ideal environment for melanocyte differentiation. It is a fully supplemented, frozen, and ready to use culture medium. It does not contain or antibiotics / antimycotics and is free of PMA and TPA.It differs from standard melanocyte media, which contain a mixture of signals and aim to provide both proliferation and melanin expression in parallel. However, the cells do not receive such mixed signals in vivo and are unable to provide both these behaviours optimally at the same time.
As a result of this focused formulation, CnT-PR-MD delivers 2.5x more melanin and increased dendricity compared with the proliferative CnT-40 medium.
CnT-PR-MD may also be used in conjunction with the CnT-PR-MH Melanocyte Homeostasis medium when conducting melanocyte whitening assays.
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Thawing, seeding, and passaging protocols are particularly important for optimal cell growth. Please visit our Protocols Page for our recommendations.
It can easily be upgraded for clinical applications. Contact us at email@example.com for further details and pricing.
|Essential Role for Integrin-Linked Kinase in Melanoblast Colonization of the Skin||Melissa Crawford, Valerie Leclerc, Kevin Barr, Lina Dagnino||2020||Melanocyte|