Publications

Sonja Harjuntausta et al.

(2026)

— Sci Rep

Exploring the impact of human pluripotent stem cell heterogeneity on corneal limbal stem cell differentiation outcomes

Michael J. Edel et al.

(2025)

— Stem Cells Dev

An Optimized Method to Produce Human-Induced Pluripotent Stem Cell-Derived Limbal Stem Cells Easily Adaptable for Clinical Use

Maija Kauppila et al.

(2025)

— Acta Biomaterialia

Compartmentalized 3D bioprinting of the limbal niche with distinct hPSC-LSC subpopulations for corneal disease modeling

Marla Dubau et al.

(2025)

— J Tissue Eng

Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances

Tong Xie et al.

(2025)

— Cosmetics

Human Induced Pluripotent Stem Cells-Derived Reconstructed Epidermal Skin Model as an Alternative Model for Skin Irritation

Masato Nakagawa et al.

(2025)

— Sci Rep

MDM4 enables efficient human iPS cell generation from PBMCs using synthetic RNAs

Paula Puistola et al.

(2025)

— Bioprinting

Multi-material 3D bioprinting of human stem cells to engineer complex human corneal structures with stroma and epithelium

Rei Kamuro et al.

(2025)

— Commun Biol

PAX6-dependent differentiation landscape of ocular surface epithelium via single-cell RNA sequencing in hiPSC-derived ocular developmental organoid

Hyewon Shin et al.

(2025)

— PLoS One

Skin irritation testing using human iPSCs derived 3D skin equivalent model

Amar J. Azad et al.

(2025)

— Stem Cell Res & Ther

Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems

Gabriella A. Bertaccini et al.

(2025)

— Nat Commun

Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology

Marla Dubau et al.

(2024)

— J Tissue Eng

Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach

Canwei Zhang et al.

(2024)

— Life Med

Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system

Juan J. Novoa et al.

(2024)

— Cytotherapy

Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products

Benjamin J. Steinbeck et al.

(2024)

— J Investig Dermatol

Twin Prime Editing Mediated Exon Skipping/Reinsertion for Restored Collagen VII Expression in Recessive Dystrophic Epidermolysis Bullosa

Masahiro Kitao et al.

(2023)

— iScience

Identification of BST2 as a conjunctival epithelial stem/progenitor cell marker

Maija Kauppila et al.

(2023)

— Adv Healthcare Mater

Toward Corneal Limbus In Vitro Model: Regulation of hPSC-LSC Phenotype by Matrix Stiffness and Topography During Cell Differentiation Process

Sophie Domingues et al.

(2022)

— Cells

Clinical Grade Human Pluripotent Stem Cell-Derived Engineered Skin Substitutes Promote Keratinocytes Wound Closure In Vitro

Ryuhei Hayashi et al.

(2022)

— Nature

Generation of 3D lacrimal gland organoids from human pluripotent stem cells

Julien Coutier et al.

(2022)

— J Investig Dermatol

Human-Induced Pluripotent Stem Cell-Derived Keratinocytes, a Useful Model to Identify and Explore the Pathological Phenotype of Epidermolysis Bullosa Simplex

Maija Kauppila et al.

(2022)

— nano select

Multi-parametric surface plasmon resonance-based intake quantification of label-free light-activated nanoparticles by therapeutic limbal stem cells for corneal blindness

Naresh Polisetti et al.

(2022)

— Cells

Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells

Meri Vattulainen et al.

(2021)

— Stem Cell Res & Ther

Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5+ and ∆Np63α+ cells cells with limbal cell characteristics and high wound healing capacity

Kimihito Nomi et al.

(2021)

— Cell Rep

Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs

Dulce Lima Cunha et al.

(2021)

— Int J Mol Sci

hiPSC-Derived Epidermal Keratinocytes from Ichthyosis Patients Show Altered Expression of Cornification Markers

Shinya Watanabe et al.

(2021)

— iScience

Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities

Changbin Sun et al.

(2021)

— Cell & Bioscience

Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells

Munenari Itoh et al.

(2020)

— J Dermatological Sci

Footprint-free gene mutation correction in induced pluripotent stem cell (iPSC) derived from recessive dystrophic epidermolysis bullosa (RDEB) using the CRISPR/Cas9 and piggyBac transposon system

Sonya Ruiz-Torres et al.

(2020)

— Cell Stem Cell

Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

Yuki Kobayashi et al.

(2020)

— Stem Cell Res

Ocular Surface Ectoderm Instigated by WNT inhibition and BMP4

Meri Vattulainen et al.

(2019)

— Stem Cell Res & Ther

Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential

Shun Shibata et al.

(2019)

— Regenerative Ther

The secretome of adipose-derived mesenchymal stem cells attenuates epithelial-mesenchymal transition in human corneal epithelium

Anni Sorkio et al.

(2018)

— Biomaterials

Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks

Shun Shibata et al.

(2018)

— Cell Rep

Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages

Ryuhei Hayashi et al.

(2017)

— Nat Protoc

Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells

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