Publications

Sonja Harjuntausta et al.

(2026)

— Sci Rep

Exploring the impact of human pluripotent stem cell heterogeneity on corneal limbal stem cell differentiation outcomes

Sonja Dorfer et al.

(2026)

— J Invest Dermatol

Transcriptome-guided drug repurposing identifies selumetinib for an aggressive epithelial cancer

Se-jeong Kim et al.

(2025)

— Adv Healthcare Mater

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Yuri Watanabe et al.

(2025)

— Eur J Dentistry

A Comparative Analysis of Cell Proliferation and Wound Closure in Cultured Gingival Epithelial Cells Using Plasma Rich in Growth Factors and Platelet-Rich Plasma Containing Leukocytes

Angela L. Maloney et al.

(2025)

— Front Microbiomes

A Multi-Strain Human Skin Microbiome Model Provides a Testbed for Disease Modeling

E. Cate Wisdom et al.

(2025)

— Bioengineering

A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal-Epidermal Composites Using Non-Adherent Microwell Arrays

Shuji Yamamura et al.

(2025)

— J Investig Dermatol

Aging-Associated Mitochondrial Decline Accelerates Skin Aging and Obesity

Qin Hu et al.

(2025)

— Archives Oral Biol

Akkermansia muciniphila enhances mucosal immunity against porphyromonas gingivalis

Michael J. Edel et al.

(2025)

— Stem Cells Dev

An Optimized Method to Produce Human-Induced Pluripotent Stem Cell-Derived Limbal Stem Cells Easily Adaptable for Clinical Use

Xuan Li et al.

(2025)

— ACS Nano

Berberine-Functionalized Bismuth-Doped Carbon Dots in a Pathogen-Responsive Hydrogel System: A Multifaceted Approach to Combating Periodontal Diseases

Hyun Jung Lee et al.

(2025)

— Invest Ophthalmol Vis Sci

Characterization of LGR5 as a Definitive and Functional Marker for Human Limbal Epithelial Stem Cells

Lucas Schoenfeldt et al.

(2025)

— EMBO Mol Med

Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan

Jule Riebelmann et al.

(2025)

— Front Immunol

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling

Gizem Coşar Kutluoğlu et al.

(2025)

— Wound Repair Regeneration

Comparison of dermal and eschar fibroblasts in full skin equivalents

Maija Kauppila et al.

(2025)

— Acta Biomaterialia

Compartmentalized 3D bioprinting of the limbal niche with distinct hPSC-LSC subpopulations for corneal disease modeling

Karolina Niska et al.

(2025)

— Toxicology Vitro

Cytotoxicity of ZnO nanoparticles in human melanocyte cells in the presence or absence of UV radiation: A preliminary comparative study with TiO2 nanoparticles

Marla Dubau et al.

(2025)

— J Tissue Eng

Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances

Omera Bi et al.

(2025)

— Exp Dermatol

Do Melanocytes Have a Role in Controlling Epidermal Bacterial Colonisation and the Skin Microbiome?

Ricardo Fróis-Martins et al.

(2025)

— Nat Microbiol

Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice

Atsushi Oka et al.

(2025)

— J Stomatology, Soc Japan

Effect of Vascular Endothelial Growth Factor/Hepatocyte Growth Factor Signaling Inhibition on Peri-implantitis-associated Fibroblasts

Alessia Cavallo et al.

(2025)

— Front Physiology

Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes

Siavash Rahimi et al.

(2025)

— Curr Protoc

Efficient On-Column Removal of Endotoxin from Immunoglobulins Such as AK23

Rima Nuwayhid et al.

(2025)

— Front Bioeng Biotechnol

Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro

Jin Hwan Kim et al.

(2025)

— Free Radic Biol Med

Exopolysaccharide from Lacticaseibacillus rhamnosus IR06 as a potential postbiotics attenuates photoaging through regulation of MAPK and NF-κB signaling

Justin C. Rudd et al.

(2025)

— Nat Commun

Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier

Mukta Basu et al.

(2025)

— Cell Death Disease

Genes driving three-dimensional growth of immortalized cells and cancer

Bishal Tandukar et al.

(2025)

— Nat Commun

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

Qin Hu et al.

(2025)

— J Tissue Eng

Gum-on-a-Chip Exploring Host-Microbe Interactions: Periodontal Disease Modeling and Drug Discovery

Yin Li et al.

(2025)

— J Invest Dermatol

High-Resolution Spatial Transcriptomics Unveils Spatially Resolved Gene Modules and Fatty Acid Metabolism Dysregulation in Human Skin Aging

Agnieszka Gogler et al.

(2025)

— Cell Death Disease

HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines

Dominic Rütsche et al.

(2025)

— Small Methods

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo-Epidermal Skin Substitutes

Tong Xie et al.

(2025)

— Cosmetics

Human Induced Pluripotent Stem Cells-Derived Reconstructed Epidermal Skin Model as an Alternative Model for Skin Irritation

Leslie Hertereau et al.

(2025)

— JID Innovations

Human keratinocytes exhibit limited potential for SARS-CoV-2 infection despite ACE2 and mature cathepsin L expression

Anne Jamet et al.

(2025)

— Sci Transl Med

Immune response and clinical severity are shaped by skin-adapted Staphylococcus aureus in chronically infected patients

Haruna Kimura et al.

(2025)

— Nat Commun

Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models

Farzan Solimani et al.

(2025)

— Inflammation

Inhibition of the JAK/STAT signaling pathway suggests a protective effect against acantholysis in pemphigus

Bindeshwar Sah et al.

(2025)

— Int J Dermatol

Loss of CELF2 promotes skin tumorigenesis and increases drug resistance

Damien Adam et al.

(2025)

— ERJ Open Res

Low molecular weight hyaluronic acid improves regeneration of CF airway epithelium

Masato Nakagawa et al.

(2025)

— Sci Rep

MDM4 enables efficient human iPS cell generation from PBMCs using synthetic RNAs

Pedram Gerami et al.

(2025)

— Sci Adv

Molecular effects of indoor tanning

Paula Puistola et al.

(2025)

— Bioprinting

Multi-material 3D bioprinting of human stem cells to engineer complex human corneal structures with stroma and epithelium

Berenice Fischer et al.

(2025)

— J Investig Dermatol

NOD2-induced IκBζ mediates a protective host response against epicutaneous Staphylococcus aureus infection

Laura Schwartz et al.

(2025)

— iScience

Obesity promotes urinary tract infection by disrupting bladder focal adhesion kinase signaling

Rei Kamuro et al.

(2025)

— Commun Biol

PAX6-dependent differentiation landscape of ocular surface epithelium via single-cell RNA sequencing in hiPSC-derived ocular developmental organoid

J�lia Capp Zilles et al.

(2025)

— ACS Omega

Polymeric Nanocapsules Containing Kojic Acid Dipalmitate and Rosehip Oil: Development and Evaluation of Preliminary Efficacy and Safety for Skin Whitening

Laure M. G. Petit et al.

(2025)

— Front Cell Developmental Biol

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD

Markus Hierl et al.

(2025)

— Mol Ther

Prime editing as a promising therapeutic strategy for junctional epidermolysis bullosa

Shinobu Nakanishi et al.

(2025)

— STAR Protoc

Protocol for odorant-binding protein 2A gene knockdown by dual siRNA transfection in a three-dimensional human epidermal equivalent model

Aaron Simoni et al.

(2025)

— Life Sci Alliance

PTEN modulates urinary tract infection susceptibility and shapes urothelial antibacterial defenses

Francisco J. Roa et al.

(2025)

— Cancer Res Commun

Repurposing amiodarone for bladder cancer treatment

Sonja Dorfer et al.

(2025)

— J Dermatol

Repurposing diacerein for the treatment of chronic wounds in recessive-dystrophic epidermolysis bullosa patients by modulating matrix metalloproteinase-9 expression

Hokoru Yoshioka et al.

(2025)

— Investig Ophthalmol & Visual Sci

Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization

Charles S. Kirby et al.

(2025)

— J Clin Investig

RNase L represses hair follicle regeneration through altered innate immune signaling

Adrien Maupas et al.

(2025)

— PLoS One

Roscovitine enhances the bactericidal activity of the airway surface liquid of the cystic fibrosis bronchial epithelium but does not protect against Pseudomonas aeruginosa infection

Hirokazu Kubo et al.

(2025)

— PLoS One

Sage extract and ascorbic acid derivative inhibit melanogenesis via downregulating keratinocyte-derived GM-CSF

ChenRongRong Cai et al.

(2025)

— J Virology

Sensing of SARS-CoV-2-infected cells by plasmacytoid dendritic cells is modulated via an interplay between CD54/ICAM-1 and CD11a/LFA-1 αL integrin

Luca Pontiggia et al.

(2025)

— Exp Cell Res

Simple method for the production of rete ridges in human dermo-epidermal skin substitutes

Hyewon Shin et al.

(2025)

— PLoS One

Skin irritation testing using human iPSCs derived 3D skin equivalent model

C�line David et al.

(2025)

— Cell Death Dis

Small-molecule inhibitor of C-terminal HSP90 dimerization modulates autophagy and functions synergistically with mTOR inhibition to kill cisplatin-resistant cancer cells

Youngrok Park et al.

(2025)

— PLoS One

STAG2 regulates polycomb and differentiation in urothelial precursors and bladder cancer

Guillermo Nevot et al.

(2025)

— Cell Systems

Synthetically programmed antioxidant delivery by a domesticated skin commensal

Tzu-Hsuan Chang et al.

(2025)

— Front Immunol

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

Daniel C. Stewart et al.

(2025)

— J Investig Dermatol

Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing

Gareth Hazell et al.

(2025)

— Int J Obesity

Ultraviolet exposure of mice fed a high fat diet reduces weight gain and markers of liver disease progression

Amar J. Azad et al.

(2025)

— Stem Cell Res & Ther

Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems

Daigo Inoue et al.

(2025)

— Int J Mol Sci

UVB-/Age-Dependent Upregulation of Inflammatory Factor Interleukin-6 Receptor (IL-6R) in Keratinocytes Stimulates Melanocyte Dendricity

George H. Hatton et al.

(2025)

— Sci Adv

Virus-induced APOBEC3 transmutagenesis in bladder cancer initiation

Gabriella A. Bertaccini et al.

(2025)

— Nat Commun

Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology

Taeeun Kim et al.

(2025)

— Polymers

Wound Healing in Human Skin Equivalents Reconstructed with Biopolymers Under Fine-Dust Exposure

Cl�ment Quintard et al.

(2024)

— Nat Commun

A microfluidic platform integrating functional vascularized organoids-on-chip

Paul Kischkel et al.

(2024)

— Exp Dermatol

A novel 3D skin model for in vitro testing of wound dressings

K. Brandmair et al.

(2024)

— Toxicology

A novel three-dimensional Nrf2 reporter epidermis model for skin sensitization assessment

Rima Nuwayhid et al.

(2024)

— MDPI biomedicines

A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent

Marla Dubau et al.

(2024)

— J Tissue Eng

Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach

Wenyan Kang et al.

(2024)

— Dental Mater

An integrated preventive and therapeutic magnetic nanoparticle loaded with rhamnolipid and vancomycin for combating subgingival biofilms

Mayuko Endo et al.

(2024)

— Bioscience, Biotechnology, Biochem

Analysis on promotive effect of rocking culture on keratinocyte differentiation in 3-dimensional reconstitution human epidermis

Maxwell B. Nagarajan et al.

(2024)

— Biofabrication

Biomimetic human skin model patterned with rete ridges

Dominik Imfeld et al.

(2024)

— Int J Cosmetic Sci

Boosting of Retinol Activity Using Novel Lecithin: Retinol Acyltransferase Inhibitors

Katja Knapp et al.

(2024)

— Cell Rep Med

Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection

Hae Jin Lee et al.

(2024)

— Int J Radiation Biol

Comparison of Cellular Responses to Ionizing Radiation in Keratinocytes Isolated from Healthy Donors and Type II Diabetes Patients

Dina Mikimoto et al.

(2024)

— Biofabrication

Culture insert device with perfusable microchannels enhances in vitro skin model development and barrier function assessment

Canwei Zhang et al.

(2024)

— Life Med

Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system

Petra Doerfler et al.

(2024)

— J Investig Dermatol

Development of a Cellular Assay as a Personalized Model for Testing Chronic Wound Therapeutics

Maitreyi Rathod et al.

(2024)

— J Cell Biol

DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5

Anastasiya V. Kosykh et al.

(2024)

— Int J Mol Sci

EBS in Children with De Novo Pathogenic Variants Disturbing Krt14

Kaori Kanemaru et al.

(2024)

— Biochem Biophysical Res Commun

Epidermal loss of Bcl6 exacerbates MC903-induced atopic dermatitis-like skin inflammation

Manuel Chac�n et al.

(2024)

— Toxicology Vitro

Evaluating the QileX-RhE skin corrosion test for chemical subcategorization in accordance with OECD TG 431

Yuki Takezawa et al.

(2024)

— Exp Eye Res

Experimental interventions attenuate a conjunctival epidermal metaplasia model

Sybille Hasse et al.

(2024)

— Int J Mol Sci

Exploring the Influence of Cold Plasma on Epidermal Melanogenesis In Situ and In Vitro

Seung Jin Jang et al.

(2024)

— Viruses

Genome-Wide Transcriptional Roles of KSHV Viral Interferon Regulatory Factors in Oral Epithelial Cells

Lisa M. Sevilla et al.

(2024)

— Cell Death Disease

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes

Laure M.G. Petit et al.

(2024)

— Heliyon

Glypican-3 is a key tuner of the Hedgehog pathway in COPD

Juan J. Novoa et al.

(2024)

— Cytotherapy

Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products

Katharina Bier et al.

(2024)

— J Investig Dermatol

IL-26 Potentiates Type 2 Skin Inflammation in the Presence of IL-1β

Farah Mansour et al.

(2024)

— Front Cell Developmental Biol

Immortalization of patient-derived lip cells for establishing 3D lip models

Maximilian Kollmuss et al.

(2024)

— Polymers

In Vitro Cytotoxic and Inflammatory Response of Gingival Fibroblasts and Oral Mucosal Keratinocytes to 3D Printed Oral Devices

Julia Scheurer et al.

(2024)

— Disease Models & Mechanisms

Inflammatory skin disease modeling using 3D human skin equivalents

Laura Schwartz et al.

(2024)

— Cell Rep

Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

Enrica Flori et al.

(2024)

— Cells

JAK/STAT Inhibition Normalizes Lipid Composition in 3D Human Epidermal Equivalents Challenged with Th2 Cytokines

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