Sonja Harjuntausta et al.
(2026)
— Sci Rep
Exploring the impact of human pluripotent stem cell heterogeneity on corneal limbal stem cell differentiation outcomes
Se-jeong Kim et al.
(2025)
— Adv Healthcare Mater
A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants
Michael J. Edel et al.
(2025)
— Stem Cells Dev
An Optimized Method to Produce Human-Induced Pluripotent Stem Cell-Derived Limbal Stem Cells Easily Adaptable for Clinical Use
Hyun Jung Lee et al.
(2025)
— Invest Ophthalmol Vis Sci
Characterization of LGR5 as a Definitive and Functional Marker for Human Limbal Epithelial Stem Cells
Maija Kauppila et al.
(2025)
— Acta Biomaterialia
Compartmentalized 3D bioprinting of the limbal niche with distinct hPSC-LSC subpopulations for corneal disease modeling
Masato Nakagawa et al.
(2025)
— Sci Rep
MDM4 enables efficient human iPS cell generation from PBMCs using synthetic RNAs
Paula Puistola et al.
(2025)
— Bioprinting
Multi-material 3D bioprinting of human stem cells to engineer complex human corneal structures with stroma and epithelium
Rei Kamuro et al.
(2025)
— Commun Biol
PAX6-dependent differentiation landscape of ocular surface epithelium via single-cell RNA sequencing in hiPSC-derived ocular developmental organoid
Hokoru Yoshioka et al.
(2025)
— Investig Ophthalmol & Visual Sci
Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization
Krzysztof Pietryga et al.
(2024)
— Sci Rep
Bio-printing method as a novel approach to obtain a fibrin scaffold settled by limbal epithelial cells for corneal regeneration
Canwei Zhang et al.
(2024)
— Life Med
Deciphering the dynamic single-cell transcriptional landscape in the ocular surface ectoderm differentiation system
Yuki Takezawa et al.
(2024)
— Exp Eye Res
Experimental interventions attenuate a conjunctival epidermal metaplasia model
Kathryn C. Davidson et al.
(2024)
— Sci Rep
Single nuclei transcriptomics of the in situ human limbal stem cell niche
Maija Kauppila et al.
(2024)
— Ocular Surface
Whole mount immunofluorescence analysis of fresh and stored human donor corneas highlights changes in limbal characteristics during storage
Berbang Meshko et al.
(2023)
— Cells
ABCB5+ Limbal Epithelial Stem Cells Inhibit Developmental but Promote Inflammatory (Lymph) Angiogenesis While Preventing Corneal Inflammation
Naresh Polisetti et al.
(2023)
— Int J Mol Sci
Efficient Isolation and Expansion of Limbal Melanocytes for Tissue Engineering
Masahiro Kitao et al.
(2023)
— iScience
Identification of BST2 as a conjunctival epithelial stem/progenitor cell marker
Naresh Polisetti et al.
(2023)
— MDPI Cells
PAX6 Expression Patterns in the Adult Human Limbal Stem Cell Niche
Thomas Volatier et al.
(2023)
— Biol
Short-Term UVB Irradiation Leads to Persistent DNA Damage in Limbal Epithelial Stem Cells, Partially Reversed by DNA Repairing Enzymes
Maija Kauppila et al.
(2023)
— Adv Healthcare Mater
Toward Corneal Limbus In Vitro Model: Regulation of hPSC-LSC Phenotype by Matrix Stiffness and Topography During Cell Differentiation Process
Alice Rocha Teixeira Netto et al.
(2023)
— Methods Protoc
Two Methods for the Isolation and Cultivation of Porcine Primary Corneal Cells
Tarek Bayyoud et al.
(2022)
— Graefe's Archive Clin Exp Ophthalmol
Absence of detectable SARS-CoV-2 replication in ex vivo cultured cornea and cornea-derived epithelial cells
Gabriele Saccu et al.
(2022)
— Cells
Bone Marrow Mesenchymal Stromal/Stem Cell-Derived Extracellular Vesicles Promote Corneal Wound Repair by Regulating Inflammation and Angiogenesis
M. Domdey et al.
(2022)
— Stem Cell Res
Consecutive dosing of UVB irradiation induces loss of ABCB5 expression and activation of EMT and fibrosis proteins in limbal epithelial cells similar to pterygium epithelium
Ryuhei Hayashi et al.
(2022)
— Nature
Generation of 3D lacrimal gland organoids from human pluripotent stem cells
Shen Li et al.
(2022)
— Int J Mol Sci
Identification, Isolation, and Characterization of Melanocyte Precursor Cells in the Human Limbal Stroma
Manuel Chac�n et al.
(2022)
— Bioelectrochemistry
Impedance-based non-invasive assay for ocular damage prediction on in vitro 3D reconstructed human corneal epithelium
Maija Kauppila et al.
(2022)
— nano select
Multi-parametric surface plasmon resonance-based intake quantification of label-free light-activated nanoparticles by therapeutic limbal stem cells for corneal blindness
Naresh Polisetti et al.
(2022)
— Cells
P-Cadherin Is Expressed by Epithelial Progenitor Cells and Melanocytes in the Human Corneal Limbus
Naresh Polisetti et al.
(2022)
— Cells
Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells
Meri Vattulainen et al.
(2021)
— Stem Cell Res & Ther
Corneal epithelial differentiation of human pluripotent stem cells generates ABCB5+ and ∆Np63α+ cells cells with limbal cell characteristics and high wound healing capacity
Nihal Kaplan et al.
(2021)
— FASEB J
Eph signaling is regulated by miRNA-210: Implications for corneal epithelial repair
Kimihito Nomi et al.
(2021)
— Cell Rep
Generation of functional conjunctival epithelium, including goblet cells, from human iPSCs
Shinya Watanabe et al.
(2021)
— iScience
Human iPS cells engender corneal epithelial stem cells with holoclone-forming capabilities
Changbin Sun et al.
(2021)
— Cell & Bioscience
Time-course single-cell RNA sequencing reveals transcriptional dynamics and heterogeneity of limbal stem cells derived from human pluripotent stem cells
Pattama Ekpo et al.
(2020)
— PLoS One
Characterization of limbal explant sites: Optimization of stem cell outgrowth in in vitro culture
Junyi Wang et al.
(2020)
— Adv Ther
HDL Nanoparticles Have Wound Healing and Anti-Inflammatory Properties and Can Topically Deliver miRNAs
Naresh Polisetti et al.
(2020)
— Sci Rep
Isolation and enrichment of melanocytes from human corneal limbus using CD117 (c-Kit) as selection marker
Yuki Kobayashi et al.
(2020)
— Stem Cell Res
Ocular Surface Ectoderm Instigated by WNT inhibition and BMP4
Mayumi Ueta et al.
(2020)
— Sci Rep
Regulation of gene expression by miRNA-455-3p, upregulated in the conjunctival epithelium of patients with Stevens-Johnson syndrome in the chronic stage
Rozaliya Hristova et al.
(2020)
— J Int Translational Med
Treatment of limbal stem cell deficiency in the setting of neurotrophic keratopathy
Michel Haagdorens et al.
(2019)
— Stem Cells Int
In Vitro Cultivation of Limbal Epithelial Stem Cells on Surface-Modified Crosslinked Collagen Scaffolds
Meri Vattulainen et al.
(2019)
— Stem Cell Res & Ther
Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential
Jeongyun Seo et al.
(2019)
— Nat Med
Multiscale reverse engineering of the human ocular surface
Shun Shibata et al.
(2019)
— Regenerative Ther
The secretome of adipose-derived mesenchymal stem cells attenuates epithelial-mesenchymal transition in human corneal epithelium
Peng Xu et al.
(2018)
— Translational Vision Sci & Technol
A New in Vitro Model of GDLD by Knocking Out TACSTD2 and Its Paralogous Gene EpCAM in Human Corneal Epithelial Cells
Anni Sorkio et al.
(2018)
— Biomaterials
Human stem cell based corneal tissue mimicking structures using laser-assisted 3D bioprinting and functional bioinks
Shun Shibata et al.
(2018)
— Cell Rep
Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages
Ryuhei Hayashi et al.
(2017)
— Nat Protoc
Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells
