Publications

Sonja Dorfer et al.

(2026)

— J Invest Dermatol

Transcriptome-guided drug repurposing identifies selumetinib for an aggressive epithelial cancer

Angela L. Maloney et al.

(2025)

— Front Microbiomes

A Multi-Strain Human Skin Microbiome Model Provides a Testbed for Disease Modeling

E. Cate Wisdom et al.

(2025)

— Bioengineering

A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal-Epidermal Composites Using Non-Adherent Microwell Arrays

Shuji Yamamura et al.

(2025)

— J Investig Dermatol

Aging-Associated Mitochondrial Decline Accelerates Skin Aging and Obesity

Erez N. Baruch et al.

(2025)

— Nature

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy

Esther Hindriks et al.

(2025)

— Vet Immunol Immunopathology

Cancer-testis antigen expression in canine melanoma and healthy tissues

Lucas Schoenfeldt et al.

(2025)

— EMBO Mol Med

Chemical reprogramming ameliorates cellular hallmarks of aging and extends lifespan

Jule Riebelmann et al.

(2025)

— Front Immunol

Commensal Staphylococci attenuate Staphylococcus aureus skin colonization and inflammation via AHR-dependent signaling

Gizem Coşar Kutluoğlu et al.

(2025)

— Wound Repair Regeneration

Comparison of dermal and eschar fibroblasts in full skin equivalents

Karolina Niska et al.

(2025)

— Toxicology Vitro

Cytotoxicity of ZnO nanoparticles in human melanocyte cells in the presence or absence of UV radiation: A preliminary comparative study with TiO2 nanoparticles

Akira Matsuda et al.

(2025)

— J Vet Med Sci

Daily topical application of chlorhexidine gluconate to the skin in dogs and its impact on skin barriers and cytotoxicity

Jing Luo et al.

(2025)

— Biochem Biophysical Res Commun

Deficiency of inducible nitric oxide synthase (iNOS) enhances MC903-induced atopic dermatitis-like inflammation in mice

Marla Dubau et al.

(2025)

— J Tissue Eng

Development of an iPSC-derived immunocompetent skin model for identification of skin sensitizing substances

Omera Bi et al.

(2025)

— Exp Dermatol

Do Melanocytes Have a Role in Controlling Epidermal Bacterial Colonisation and the Skin Microbiome?

Michael Koch et al.

(2025)

— Disease Models & Mechanisms

Dose-dependent effects of Nrf2 on the epidermis in chronic skin inflammation

Ricardo Fróis-Martins et al.

(2025)

— Nat Microbiol

Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice

Alessia Cavallo et al.

(2025)

— Front Physiology

Effects of Th1/Th17 and Th2 cytokines on lipid metabolism in differentiated keratinocytes

Siavash Rahimi et al.

(2025)

— Curr Protoc

Efficient On-Column Removal of Endotoxin from Immunoglobulins Such as AK23

Rima Nuwayhid et al.

(2025)

— Front Bioeng Biotechnol

Engineering a 3D wounded skin equivalent to study early inflammatory and regenerative responses in vitro

Jin Hwan Kim et al.

(2025)

— Free Radic Biol Med

Exopolysaccharide from Lacticaseibacillus rhamnosus IR06 as a potential postbiotics attenuates photoaging through regulation of MAPK and NF-κB signaling

Justin C. Rudd et al.

(2025)

— Nat Commun

Flower dependent trafficking of lamellar bodies facilitates maturation of the epidermal barrier

Bishal Tandukar et al.

(2025)

— Nat Commun

Genetic evolution of keratinocytes to cutaneous squamous cell carcinoma

Yin Li et al.

(2025)

— J Invest Dermatol

High-Resolution Spatial Transcriptomics Unveils Spatially Resolved Gene Modules and Fatty Acid Metabolism Dysregulation in Human Skin Aging

Agnieszka Gogler et al.

(2025)

— Cell Death Disease

HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines

Dominic Rütsche et al.

(2025)

— Small Methods

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo-Epidermal Skin Substitutes

Tong Xie et al.

(2025)

— Cosmetics

Human Induced Pluripotent Stem Cells-Derived Reconstructed Epidermal Skin Model as an Alternative Model for Skin Irritation

Leslie Hertereau et al.

(2025)

— JID Innovations

Human keratinocytes exhibit limited potential for SARS-CoV-2 infection despite ACE2 and mature cathepsin L expression

Xingli Zhou et al.

(2025)

— Burns & Trauma

Human Urine-Derived Stem Cells Rescue Cutaneous Manifestation and Suppress Inflammation and Fibrosis In Vitro and in a Mouse Model of Recessive Dystrophic Epidermolysis Bullosa

Kyungsook Jung et al.

(2025)

— Vet Sci

IFN-γ/TNF-α Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes

Anne Jamet et al.

(2025)

— Sci Transl Med

Immune response and clinical severity are shaped by skin-adapted Staphylococcus aureus in chronically infected patients

Lizette M. Cortes et al.

(2025)

— Front Allergy

Impaired cell viability and mitochondrial respiration by disperse textile dyes

Morgan Detering et al.

(2025)

— BMC Complementary Med Therapies

In vitro characterization of potential botanicals to reduce infection and improve the rate of wound healing in humans and canines

Mengke Sun et al.

(2025)

— J Invest Dermatol

Inducible Nitric Oxide Deficiency Attenuates Necroptosis in Psoriasis-Like Dermatitis in Mice by Reducing Oxidative Stress

Haruna Kimura et al.

(2025)

— Nat Commun

Inhibition of formyl peptide receptor-1-mediated cell death as a therapy for lethal cutaneous drug reactions in preclinical models

Farzan Solimani et al.

(2025)

— Inflammation

Inhibition of the JAK/STAT signaling pathway suggests a protective effect against acantholysis in pemphigus

Shinya Taguchi et al.

(2025)

— Nat Commun

Keratinocyte-specific angiotensin II receptor-associated protein deficiency exacerbates angiotensin II-dependent hypertension via activation of the skin renin-angiotensin system

Bindeshwar Sah et al.

(2025)

— Int J Dermatol

Loss of CELF2 promotes skin tumorigenesis and increases drug resistance

Agata Lichawska-Cieslar et al.

(2025)

— Cell Commun Signaling

MCPIP3 orchestrates the balance of epidermal proliferation and differentiation

Keying Guo et al.

(2025)

— Cell Mol Life Sci

Mechanisms of cortical microtubule organization in epidermal keratinocytes

Pedram Gerami et al.

(2025)

— Sci Adv

Molecular effects of indoor tanning

Berenice Fischer et al.

(2025)

— J Investig Dermatol

NOD2-induced IκBζ mediates a protective host response against epicutaneous Staphylococcus aureus infection

J�lia Capp Zilles et al.

(2025)

— ACS Omega

Polymeric Nanocapsules Containing Kojic Acid Dipalmitate and Rosehip Oil: Development and Evaluation of Preliminary Efficacy and Safety for Skin Whitening

Markus Hierl et al.

(2025)

— Mol Ther

Prime editing as a promising therapeutic strategy for junctional epidermolysis bullosa

Shinobu Nakanishi et al.

(2025)

— STAR Protoc

Protocol for odorant-binding protein 2A gene knockdown by dual siRNA transfection in a three-dimensional human epidermal equivalent model

Sonja Dorfer et al.

(2025)

— J Dermatol

Repurposing diacerein for the treatment of chronic wounds in recessive-dystrophic epidermolysis bullosa patients by modulating matrix metalloproteinase-9 expression

Charles S. Kirby et al.

(2025)

— J Clin Investig

RNase L represses hair follicle regeneration through altered innate immune signaling

Hirokazu Kubo et al.

(2025)

— PLoS One

Sage extract and ascorbic acid derivative inhibit melanogenesis via downregulating keratinocyte-derived GM-CSF

Luca Pontiggia et al.

(2025)

— Exp Cell Res

Simple method for the production of rete ridges in human dermo-epidermal skin substitutes

Hyewon Shin et al.

(2025)

— PLoS One

Skin irritation testing using human iPSCs derived 3D skin equivalent model

Guillermo Nevot et al.

(2025)

— Cell Systems

Synthetically programmed antioxidant delivery by a domesticated skin commensal

Tzu-Hsuan Chang et al.

(2025)

— Front Immunol

Transkingdom mechanism of MAMP generation by chitotriosidase feeds oligomeric chitin from fungal pathogens and allergens into TLR2-mediated innate immune sensing

Daniel C. Stewart et al.

(2025)

— J Investig Dermatol

Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing

Gareth Hazell et al.

(2025)

— Int J Obesity

Ultraviolet exposure of mice fed a high fat diet reduces weight gain and markers of liver disease progression

Amar J. Azad et al.

(2025)

— Stem Cell Res & Ther

Unveiling tissue-specific transcriptional adaptations in iPSC-derived fibroblasts via co-culture systems

Daigo Inoue et al.

(2025)

— Int J Mol Sci

UVB-/Age-Dependent Upregulation of Inflammatory Factor Interleukin-6 Receptor (IL-6R) in Keratinocytes Stimulates Melanocyte Dendricity

Gabriella A. Bertaccini et al.

(2025)

— Nat Commun

Visualizing PIEZO1 localization and activity in hiPSC-derived single cells and organoids with HaloTag technology

Taeeun Kim et al.

(2025)

— Polymers

Wound Healing in Human Skin Equivalents Reconstructed with Biopolymers Under Fine-Dust Exposure

Cl�ment Quintard et al.

(2024)

— Nat Commun

A microfluidic platform integrating functional vascularized organoids-on-chip

Paul Kischkel et al.

(2024)

— Exp Dermatol

A novel 3D skin model for in vitro testing of wound dressings

K. Brandmair et al.

(2024)

— Toxicology

A novel three-dimensional Nrf2 reporter epidermis model for skin sensitization assessment

Bonnie C. Carney et al.

(2024)

— Front Bioscience

A Nude Mouse Model of Xenografted Hypertrophic Scar Cells to Test Therapeutics in the Skin

Rima Nuwayhid et al.

(2024)

— MDPI biomedicines

A Platform for Testing the Biocompatibility of Implants: Silicone Induces a Proinflammatory Response in a 3D Skin Equivalent

Marla Dubau et al.

(2024)

— J Tissue Eng

Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach

Mayuko Endo et al.

(2024)

— Bioscience, Biotechnology, Biochem

Analysis on promotive effect of rocking culture on keratinocyte differentiation in 3-dimensional reconstitution human epidermis

Jae-Eun Hyun et al.

(2024)

— Vet Sci

Antimicrobial Peptide Reduces Cytotoxicity and Inflammation in Canine Epidermal Keratinocyte Progenitor Cells Induced by Pseudomonas aeruginosa Infection

Maxwell B. Nagarajan et al.

(2024)

— Biofabrication

Biomimetic human skin model patterned with rete ridges

Dominik Imfeld et al.

(2024)

— Int J Cosmetic Sci

Boosting of Retinol Activity Using Novel Lecithin: Retinol Acyltransferase Inhibitors

Aeri Park et al.

(2024)

— Biomedicine & Pharmacotherapy

Celastrol regulates psoriatic inflammation and autophagy by targeting IL-17A

Hae Jin Lee et al.

(2024)

— Int J Radiation Biol

Comparison of Cellular Responses to Ionizing Radiation in Keratinocytes Isolated from Healthy Donors and Type II Diabetes Patients

Dina Mikimoto et al.

(2024)

— Biofabrication

Culture insert device with perfusable microchannels enhances in vitro skin model development and barrier function assessment

Petra Doerfler et al.

(2024)

— J Investig Dermatol

Development of a Cellular Assay as a Personalized Model for Testing Chronic Wound Therapeutics

Maitreyi Rathod et al.

(2024)

— J Cell Biol

DPM1 modulates desmosomal adhesion and epidermal differentiation through SERPINB5

Anastasiya V. Kosykh et al.

(2024)

— Int J Mol Sci

EBS in Children with De Novo Pathogenic Variants Disturbing Krt14

Kaori Kanemaru et al.

(2024)

— Biochem Biophysical Res Commun

Epidermal loss of Bcl6 exacerbates MC903-induced atopic dermatitis-like skin inflammation

Manuel Chac�n et al.

(2024)

— Toxicology Vitro

Evaluating the QileX-RhE skin corrosion test for chemical subcategorization in accordance with OECD TG 431

Sybille Hasse et al.

(2024)

— Int J Mol Sci

Exploring the Influence of Cold Plasma on Epidermal Melanogenesis In Situ and In Vitro

ASM Sakhawat Hossain et al.

(2024)

— Matrix Biol

Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice

Lisa M. Sevilla et al.

(2024)

— Cell Death Disease

Glucocorticoid receptor controls atopic dermatitis inflammation via functional interactions with P63 and autocrine signaling in epidermal keratinocytes

Juan J. Novoa et al.

(2024)

— Cytotherapy

Good Manufacturing Practice-compliant human induced pluripotent stem cells: from bench to putative clinical products

Akira Kazaoka et al.

(2024)

— Proc Natl Acad Sci U S A Nexus

HLA-B*57:01-dependent intracellular stress in keratinocytes triggers dermal hypersensitivity reactions to abacavir

Katharina Bier et al.

(2024)

— J Investig Dermatol

IL-26 Potentiates Type 2 Skin Inflammation in the Presence of IL-1β

Julia Scheurer et al.

(2024)

— Disease Models & Mechanisms

Inflammatory skin disease modeling using 3D human skin equivalents

Enrica Flori et al.

(2024)

— Cells

JAK/STAT Inhibition Normalizes Lipid Composition in 3D Human Epidermal Equivalents Challenged with Th2 Cytokines

Ivana Gabriela Reidel et al.

(2024)

— Vaccine

Liposomal co-encapsulation of a novel gemini lipopeptide and a CpG-ODN induces a strong Th1 response with the co-activation of a Th2/Th17 profile and high antibody levels

Xing Xiao et al.

(2024)

— J Cell Physiology

M1 polarization of macrophages promotes stress‐induced hair loss via interleukin‐18 and interleukin‐1β

Takeshi Tohgasaki et al.

(2024)

— Bioengineering

Machine Learning-Enhanced Estimation of Cellular Protein Levels from Bright-Field Images

Francesca Bork et al.

(2024)

— EMBO Rep

naRNA-LL37 composite DAMPs define sterile NETs as self-propagating drivers of inflammation

A Khalifa et al.

(2024)

— Stem Cells

Neuropeptide substance P alters stem cell fate to aid wound healing and promote epidermal stratification through asymmetric stem cell divisions

Kenji Namoto et al.

(2024)

— Cell Stem Cell

NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo

Katharina Kaiser et al.

(2024)

— Tissue Eng Part C: Methods.

Novel Chip for Applying Mechanical Forces on Human Skin Models Under Dynamic Culture Conditions

Valentina Salvi et al.

(2024)

— Dermatol Adv

Novel Insights into Dermal Regeneration

Julia Klermund et al.

(2024)

— Mol Ther

On- and off-target effects of paired CRISPR-Cas nickase in primary human cells

Siyi Tang et al.

(2024)

— Front Immunol

OPN promotes pro-inflammatory cytokine expression via ERK/JNK pathway and M1 macrophage polarization in Rosacea

Tomoki Nishiguchi et al.

(2024)

— J Dermatological Sci

P2X7R-primed keratinocytes are susceptible to apoptosis via GPCR-Gβγ-pERK signal pathways

Lisa Marie Fr�hlich et al.

(2024)

— Int J Cancer

PARP1 expression predicts PARP inhibitor sensitivity and correlates with metastatic potential and overall survival in melanoma

Jinghao Chen et al.

(2024)

— PLOS Comput Biol

PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration

Sara Salman et al.

(2024)

— J Photochemistry Photobiology

Pivotal roles of TRPV1 channel and Nrf2 factor in green light modulation of keratinocyte inflammatory response

Yilong Zhou et al.

(2024)

— Cell

RNA damage compartmentalization by DHX9 stress granules

Tong Xiao et al.

(2024)

— Stem Cell Res & Ther

Short cell cycle duration is a phenotype of human epidermal stem cells

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