Primary human keratinocytes play a key role in the inflammatory response by releasing a range of cytokines.

Cytokine Release

Inflammation is a key part of the aging process in vivo, and is triggered by a range of intrinsic and extrinsic stimuli.

In vitro, the inflammatory response can be measured following exposure to UV, or alternatively following challenge with lipopolysaccharide (LPS), a key component of bacterial cell walls.

Following challenge, the release of interleukins such as IL-1, IL-6, or IL-8 can be quantified by ELISA.

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