Adipocytes can be generated in vitro by differentiation of preadipocytes. They contain a large lipid droplet, surrounded by a thin layer of cytoplasm and flattened nucleus.

Lipids and Adipocytes

Adipocytes are a dominant part of the subcutaneous tissue layers.

Uneven distribution of the adpicytes in the subcutaneous layer can contribute to the formation of cellulite.

However subcutaneous adipocytes can also have a beneficial effect on the skin, and are known to improve wound healing.

As a result, adipocytes are regularly used for evaluation of an active ingredient’s ability to stimulate either lipogenesis or lipolysis.

> Back to Dermis Home